Prodew 400 pdf

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The most notable and obvious changes include the development of fine lines and wrinkles, loss of elasticity, increased sagging, loss of firmness, loss of color evenness or tone, coarse surface texture, and mottled pigmentation. Less obvious, but measurable changes which occur as skin ages or endures chronic environmental insult include a general reduction in cellular and tissue vitality, reduction in cell replication rates, reduced cutaneous blood flow, reduced moisture content, accumulated errors in structure and function, alterations in the normal regulation of common biochemical pathways, and a reduction in the skin's ability to remodel and repair itself.

Many of the alterations in appearance and function of the skin are caused by changes in the outer epidermal layer of the skin, while others are caused by changes in the lower dermis. Several different approaches can be used to treat damaged skin caused by aging, environmental factors, chemicals, or malnutrition. One approach involves the use of specific agents to directly stimulate or inhibit selected biochemical targets.

Examples include the use of retinoids to stimulate collagen and glycosaminoglycan synthesis by fibroblasts Schiltz, et al. Another approach is to use agents or processes that stimulate the rate at which the epidermis replaces itself, a process known as epidermal cell renewal.

Increases in epidermal cell renewal rates usually result from a more rapid rate of replication of epidermal basal cells, and can be caused by diverse stimuli such as chemical or physical injury, adverse environmental conditions, or direct stimulators of basal cell division.

Some examples of chemical injury include allergic or non-allergic contact irritation, pH extremes, or interaction of the stratum corneum with household or industrial chemicals or pollutants. Physical injury can include skin abrasion, friction i. Agents that directly or indirectly stimulate basal cell division include retinoids and barrier disrupters.

For example, U. Adverse environmental exposures that can result in more rapid epidermal turnover rates include UVA, UVB, and IR radiation from the sun and cold coupled with low relative humidity i. Several methods of increasing stratum corneum renewal rates have various drawbacks, such as significant irritation to the skin, skin toxicity, or low pH. In addition, most of these methods involve the invocation of chronic damage to the skin, which sets up repair mechanisms.

The present invention overcomes the deficiencies in the art by providing compositions and methods for their use that can be used to treat aged, mature, nutritionally-compromised, or environmentally-damaged skin. In one aspect of this invention, the composition comprises at least one, two, or three of the following: algae extract, sea fennel, or Codium Tomentosum extract. The composition can be formulated as a cosmetic compound. The composition can also be comprised in a cosmetic vehicle.

The cosmetic vehicle can include an emulsion, a cream, a lotion, a solution, an anhydrous base, a gel, or an ointment. The emulsion can be an oil-in-water emulsion or a water-in-oil emulsion. The solution can be an aqueous solution or hydro-alcoholic solution.

The anhydrous base can be a lipstick or a powder. The composition can be comprised in an anti-aging product or a moisturizing product. The composition can also be adapted for application at least once, twice, three, four, five, or more times a day during use.

In another aspect, the composition can be chemically compatible. The algae extract can be further defined as a green flower algae extract. The green flower algae extract can be obtained from Monostroma. The Monostroma that can be used with the present invention can include, for example, Monostroma nitidium, Monostroma zostericola, Monostroma angicava, Monostroma latissimum, Monostroma bulbosum, Monostroma arcticum, Monostroma areolatum, Monostroma fractum, Monostroma fuscum, Monostroma grevillei, Monostroma leptodermum, Monostroma quaternarium, Monostroma zostericola, Monostroma oxysperum , or Monostroma pulchrum.

In another embodiment, the algae extract can be obtained from Chlorella. The Chlorella can be selected from the group consisting of Chlorella pyrenoidosa, Chlorella regularis , and Chlorella vulgaris. In still another embodiment of this invention, the algae extract can be obtained from Ulva Lactuca. The algae extract can also include Monostroma, Chlorella , and Ulva Lactuca. In a particular aspect of this invention, the composition includes from about 0.

The composition can be chemically compatible. The composition can also be topically applied in amount effective to increase the stratum corneum turnover rate of the skin. The damaged skin can include nutritionally compromised skin or environmentally damaged skin. The environmentally damaged skin comprises skin damaged by UV light, chronic sun exposure, environmental pollutants, chemicals, disease pathologies, or smoking The composition can be further defined as a cosmetic composition.

The composition can be comprised in a cosmetic vehicle. Other aspects of the composition include those described throughout this specification. A particular aspect of the present invention includes a composition comprising Monostroma , sea fennel, Codium Tomentosum, Chlorella , and Ulva Lactuca , wherein the composition is formulated as a cosmetic compound.

Another embodiment of the invention includes a method of treating or preventing aged or damaged skin comprising topical application of a composition comprising Monostroma , sea fennel, Codium Tomentosum, Chlorella , and Ulva Lactuca , wherein the application of the composition treats or prevents aged or damaged skin.

The mixing of the components or ingredients of the disclosed compositions can form into a solution. In other embodiments, the compositions can also exist as undissolved colloidal suspensions. It is contemplated that any embodiment discussed in this specification can be implemented with respect to any method or composition of the invention, and vice versa. Furthermore, compositions and kits of the invention can be used to achieve methods of the invention.

Other objects, features and advantages of the present invention will become apparent from the following detailed description. It should be understood, however, that the detailed description and the specific examples, while indicating specific embodiments of the invention, are given by way of illustration only, since various changes and modifications within the spirit and scope of the invention will become apparent to those skilled in the art from this detailed description. Aged, nutritionally-compromised, and environmentally-damaged skin effect many people in today's society.

Fine lines, wrinkles, loss of elasticity, increased sagging, loss of firmness, loss of color eveness, course surface texture, and mottled pigmentation are just some examples of the effects of damaged skin.

Previous attempts to treat damaged skin have various drawbacks ranging from skin irritation to skin toxicity. The present invention is an effective alternative to the use of retinoid compounds or other materials currently used to treat aged or environmentally-damaged skin. The present invention discloses novel methods and compositions for treating damaged skin.

The methods and compositions disclosed in this specification provide treatments that can improve the skin's visual appearance, physiological functions, clinical properties, and biophysical properties by providing nourishment to the skin.

These and other aspect of the present invention are described in further detail below. Monostroma is a green flower algae that is known to stimulate the proliferation of fibroblast and increase extracellular matrix protein production. The genus of Monostroma has many species, including, for example, Monostroma nitidium, Monostroma zostericola, Monostroma angicava, Monostroma latissimum, Monostroma bulbosum, Monostroma arcticum, Monostroma areolatum, Monostroma fractum, Monostroma fuscum, Monostroma grevillei, Monostroma leptodermum, Monostroma quaternarium, Monostroma zostericola, Monostroma oxysperum , and Monostroma pulchrum.

These and other species of Monostroma are contemplated as being useful in the present invention. Monostroma can grow in the wild in temperate regions and is also available for purchase as an extract.

An air-dried product of Monostroma has, for example, the following composition: